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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 2
2004 1
2005 1
2006 3
2007 3
2008 4
2009 2
2011 1
2012 2
2013 3
2014 2
2015 2
2016 4
2017 1
2019 4
2022 1
2023 2
2024 0

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33 results

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Page 1
Defining the clinical validity of genes reported to cause pulmonary arterial hypertension.
Welch CL, Aldred MA, Balachandar S, Dooijes D, Eichstaedt CA, Gräf S, Houweling AC, Machado RD, Pandya D, Prapa M, Shaukat M, Southgate L, Tenorio-Castano J; ClinGen PH VCEP; Chung WK; International Consortium for Genetic Studies in Pulmonary Arterial Hypertension (PAH-ICON) at the Pulmonary Vascular Research Institute (PVRI). Welch CL, et al. Genet Med. 2023 Nov;25(11):100925. doi: 10.1016/j.gim.2023.100925. Epub 2023 Jul 5. Genet Med. 2023. PMID: 37422716
Genetic testing is currently recommended for adults diagnosed with heritable, idiopathic, anorexigen-, hereditary hemorrhagic telangiectasia-, and congenital heart disease-associated PAH, PAH with overt features of venous/capillary involvement, and all children diagnosed w …
Genetic testing is currently recommended for adults diagnosed with heritable, idiopathic, anorexigen-, hereditary hemorrhagic telangiectasia …
Cationic proteins from eosinophils bind bone morphogenetic protein receptors promoting vascular calcification and atherogenesis.
Meng Z, Zhang S, Li W, Wang Y, Wang M, Liu X, Liu CL, Liao S, Liu T, Yang C, Lindholt JS, Rasmussen LM, Obel LM, Stubbe J, Diederichsen AC, Sun Y, Chen Y, Yu PB, Libby P, Shi GP, Guo J. Meng Z, et al. Eur Heart J. 2023 Aug 1;44(29):2763-2783. doi: 10.1093/eurheartj/ehad262. Eur Heart J. 2023. PMID: 37279475 Free PMC article.
AIMS: Blood eosinophil count and eosinophil cationic protein (ECP) concentration are risk factors of cardiovascular diseases. This study tested whether and how eosinophils and ECP contribute to vascular calcification and atherogenesis. ...
AIMS: Blood eosinophil count and eosinophil cationic protein (ECP) concentration are risk factors of cardiovascular diseases. This st …
Expression of bone morphogenetic protein 4 and its receptors in the remodeling heart.
Wu X, Sagave J, Rutkovskiy A, Haugen F, Baysa A, Nygård S, Czibik G, Dahl CP, Gullestad L, Vaage J, Valen G. Wu X, et al. Life Sci. 2014 Mar 3;97(2):145-54. doi: 10.1016/j.lfs.2013.12.030. Epub 2014 Jan 4. Life Sci. 2014. PMID: 24398041
AIMS: Heart failure is associated with activation of fetal gene programs. ...We investigated if the expression of BMP4 and its receptors BMPR1a and BMPR2 were activated in post-infarction remodeling and heart failure. ...
AIMS: Heart failure is associated with activation of fetal gene programs. ...We investigated if the expression of BMP4 and its recept …
BMPR1A mutation-positive juvenile polyposis syndrome and atrial septal defect: coincidence or association?
Harris RE, Russell RK. Harris RE, et al. BMJ Case Rep. 2019 Jun 21;12(6):e229881. doi: 10.1136/bcr-2019-229881. BMJ Case Rep. 2019. PMID: 31229977 Free PMC article.
We describe the case of a 16-year-old male patient with BMPR1A mutation and incidentally detected atrial septal defect (ASD). This patient was diagnosed with BMPR1A mutation through genetic testing and was attending for routine surveillance endoscopy when ASD was in …
We describe the case of a 16-year-old male patient with BMPR1A mutation and incidentally detected atrial septal defect (ASD). This pa …
Duplication of 10q22.3-q23.3 encompassing BMPR1A and NGR3 associated with congenital heart disease, microcephaly, and mild intellectual disability.
Tang M, Yang YF, Xie L, Chen JL, Zhang WZ, Wang J, Zhao TL, Yang JF, Tan ZP. Tang M, et al. Am J Med Genet A. 2015 Dec;167A(12):3174-9. doi: 10.1002/ajmg.a.37347. Epub 2015 Sep 3. Am J Med Genet A. 2015. PMID: 26383923
We present an additional case with multiple congenital anomalies that include microcephaly, cardiac defect, and mild intellectual disability, in which a de novo interstitial 8.2-Mb duplication of 10q22.3-q23.3, including BMPR1A and NGR3, was identified by Illumina SNP arra …
We present an additional case with multiple congenital anomalies that include microcephaly, cardiac defect, and mild intellectual disability …
Isl1Cre reveals a common Bmp pathway in heart and limb development.
Yang L, Cai CL, Lin L, Qyang Y, Chung C, Monteiro RM, Mummery CL, Fishman GI, Cogen A, Evans S. Yang L, et al. Development. 2006 Apr;133(8):1575-85. doi: 10.1242/dev.02322. Development. 2006. PMID: 16556916 Free PMC article.
In both cardiac and limb progenitors, Isl1 expression is downregulated as progenitors migrate in to form either heart or limb. To investigate common heart-limb pathways in Isl1-expressing progenitors, we ablated the Type I Bmp receptor, Bmpr1a utilizing Isl1C …
In both cardiac and limb progenitors, Isl1 expression is downregulated as progenitors migrate in to form either heart or limb. To inv …
BMP7-based peptide agonists of BMPR1A protect the left ventricle against pathological remodeling induced by pressure overload.
Salido-Medina AB, Gil A, Expósito V, Martínez F, Redondo JM, Hurlé MA, Nistal JF, García R. Salido-Medina AB, et al. Biomed Pharmacother. 2022 May;149:112910. doi: 10.1016/j.biopha.2022.112910. Epub 2022 Apr 4. Biomed Pharmacother. 2022. PMID: 35616049 Free article.
BMP receptor 1A (BMPR1A) might mediate BMP7 antifibrotic effects. Herein we evaluated BMP7-based peptides, THR123 and THR184, agonists of BMPR1A, as cardioprotective drugs in a pressure overload model. ...Molecular docking suggests that both peptides bind with simil …
BMP receptor 1A (BMPR1A) might mediate BMP7 antifibrotic effects. Herein we evaluated BMP7-based peptides, THR123 and THR184, agonist …
Early increase in pulmonary vascular reactivity with overexpression of endothelin-1 and vascular endothelial growth factor in canine experimental heart failure.
Ray L, Mathieu M, Jespers P, Hadad I, Mahmoudabady M, Pensis A, Motte S, Peters IR, Naeije R, McEntee K. Ray L, et al. Exp Physiol. 2008 Mar;93(3):434-42. doi: 10.1113/expphysiol.2007.040469. Epub 2007 Nov 9. Exp Physiol. 2008. PMID: 17993509 Free article.
Heart failure is a cause of pulmonary vasoconstriction and remodelling, leading to pulmonary hypertension (PH) and decreased survival. The pathobiology of PH in heart failure remains incompletely understood. We investigated pulmonary vascular function and signalling …
Heart failure is a cause of pulmonary vasoconstriction and remodelling, leading to pulmonary hypertension (PH) and decreased survival …
Molecular mechanisms controlling the coupled development of myocardium and coronary vasculature.
Bhattacharya S, Macdonald ST, Farthing CR. Bhattacharya S, et al. Clin Sci (Lond). 2006 Jul;111(1):35-46. doi: 10.1042/CS20060003. Clin Sci (Lond). 2006. PMID: 16764556 Review.
In this review, we systematically evaluate approx. 90 mouse mutations that impair heart muscle growth during development. These studies provide genetic evidence for interactions between myocytes, endothelium and cells derived from the proepicardial organ and the neural cre …
In this review, we systematically evaluate approx. 90 mouse mutations that impair heart muscle growth during development. These studi …
MiR-15b-5p is Involved in Doxorubicin-Induced Cardiotoxicity via Inhibiting Bmpr1a Signal in H9c2 Cardiomyocyte.
Wan GX, Cheng L, Qin HL, Zhang YZ, Wang LY, Zhang YG. Wan GX, et al. Cardiovasc Toxicol. 2019 Jun;19(3):264-275. doi: 10.1007/s12012-018-9495-6. Cardiovasc Toxicol. 2019. PMID: 30535663
We employed a public miRNA and gene microarray to screen differentially expressed miRNAs (DEMs) and differentially expressed genes (DEGs) in rat cardiomyocytes, and 33 DEMs including miR-15b-5p and 237 DEGs including Bmpr1a and Gata4 were identified. The Gene ontology (GO) …
We employed a public miRNA and gene microarray to screen differentially expressed miRNAs (DEMs) and differentially expressed genes (DEGs) in …
33 results